NCI Well Connect: November 30, 2015
Dear Steve, 

DID YOU KNOW that in a recent survey of NCI Well Connect Members, when asked if our membership benefits kept them more informed about wellness than their friends, family, and coworkers, 97% said yes?

Other questions asked in the survey:
  • How would you rate our twice weekly eNewsletters? 80% Very Satisfied
  • Does a membership help you make better wellness choices? 67% Frequently
Hard to top those numbers. And that was before we started analyzing 23andMe genetic data!

If you want be ahead of the game when it comes to wellness, join our NCI Well Connect Membership Community.

Take advantage of all the benefits NCI Well Connect Membership provides for only 49.99 (from 79.99) for one year! If you sign up today, we will email you a free copy of our long-awaited IBS (Irritable Bowel Syndrome) Action PlanSign up here.

Not yet convinced? Read further. Below is what NCI Well Connect Members are reading today, including our Cancer Research Update. Enjoy!

Most of you are aware of our loyalty program that provides discounts at certain product purchase benchmarks. You may not know that rewards zero out every January 1. So get your orders in soon. Details at the end of this eNewsletter. 

Have a happy, healthy day. Steve and Bonnie
Today's NCI Well Connect
Steve Minsky
From Editor Steve Minsky
Click on the links below to be taken directly to each story. This may not work for all email services.
Read stories like these twice weekly from our award-winning eNewsletter, access two titles per month from our Action Plan Library, and book free wellness coaching sessions, all for one dollar per week with an NCI Well Connect Membership!
Well Connect Feature
Steve: Cancer Update

Breast Cancer
-In a study to evaluate the effect of diet on breast cancer incidence, women were randomly allocated to a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet (advice to reduce dietary fat).

After a 5 year follow-up, the Mediterranean diet with extra-virgin olive oil group was 3 times less likely, and the Mediterranean diet with nuts group was 2 times less likely to get breast cancer than the low-fat control group. The results, published in the November issue of JAMA Internal Medicine study, was the first of its kind.

-Higher alpha carotene, beta-carotene, lycopene and lutein/zeaxanthin levels were associated with lower breast cancer risk among premenopausal women and among all subtypes of estrogen-receptor or progesterone-receptor status. The results appeared in the October issue of British Journal of Nutrition.

-The inflammation-resolving properties and favorable effects of EPA and DHA omega-3 fatty acids on cancer proteins, as well as on the cardiovascular, bone, and central nervous system, make them excellent candidates for breast cancer prevention for individuals at increased risk as well as breast cancer survivors, according to the October issue of Breast Cancer Research.

-Electroacupuncture, in which small electric currents are applied to traditional acupuncture needles, might be more effective than gabapentin, a drug commonly used for reducing breast-cancer-related hot flashes, according to a study in the August issue ofJournal of Clinical Oncology.

-A study in the July issue of British Journal of Nutrition found there was no association between LDL-cholesterol and the risk of breast cancer. However, for the first time, evidence confirmed a statistically significant association between low HDL-cholesterol and the risk of breast cancer.

-A study in Nature suggests that the natural hormone progesterone could be used to slow the growth of some breast cancer tumors.

-A new study from Clinical Cancer Research confirmed that coffee inhibits the growth of tumors and reduces the risk of recurrence in women who have been diagnosed with breast cancer and treated with the drug tamoxifen.

Classic Hodgkin Lymphoma
Scientists in the September issue of American Journal of Epidemiology reported the first evidence showing that diets featuring high intake of desserts and sweets may increase Classic Hodgkin Lymphoma risk.

Colon Cancer
Prolonged TV watching is associated with higher colorectal cancer-specific mortality independent of leisure-time physical activity among colorectal cancer patients, according to a study in the August issue of Cancer, Causes, and Control.

Head and Neck Cancer
Higher intakes of vitamin C lower the incidence of head and neck cancers, according to a study in the July issue of American Journal of Clinical Nutrition.

Lung Cancer
According to a study in the September/October issue of Journal of the American College of Nutrition, a nutritional risk screening is crucial for positive outcomes in lung cancer patients. It is believed that of 50% of lung cancer patients have worse outcomes because of malnutrition. Early detection by a licensed health professional helped survival rate tremendously in this study of lung cancer patients.

Pancreatic Cancer
-High omega-3 fish and fish oil consumption was associated with a lower risk of pancreatic cancer in a large population, study, according to a recent study in American Journal of Clinical Nutrition.

-For several years now, researchers have been examining the effects of crocetin, derived from saffron, on pancreatic cancer. In a study just published in the journal Oncotarget, the researchers led found that crocetinic acid, a purified compound from crocetin, showed the inhibition of growth in human pancreatic cancer cells grown either in a dish or as tumors under the skin of mice.

-A study in the September issue of The Journal of Nutrition looking at how a single meal containing raw, crushed garlic acts in humans found activation of genes related to immunity and tumor protection in humans.

-University of Missouri researchers have found that luteolin, a natural compound found in herbs such as thyme and parsley as well as vegetables such as celery and broccoli, could reduce the cancer risk for women who have taken hormone replacement therapy.

-Green tea consumption was significantly inversely associated with CVD and all-cause mortality, whereas black tea consumption was significantly inversely associated with all cancer and all-cause mortality, as published in the July issue of British Journal of Nutrition.

-In the April issue of Cancer, Causes, and Control, researchers state that high folate intake during childhood may reduce the risk of childhood brain tumors.

-A compound and an enzyme that occur naturally in cruciferous vegetables -- cauliflower, cabbage, broccoli and Brussels sprouts -- may help prevent recurrence and spread of some cancers, according to a study in BMC Cancer. The precursor compound and enzyme in cruciferous vegetables combine during the chewing process to produce Phenethyl isothiocyanate (PEITC) within the body.

When cancer is treated with chemotherapy or radiation, the tumor disappears but the cancer stem cells live on. These cells are frequently resistant to conventional therapies. When scientists treated human cervical cancer stem cells with PEITC in a Petri dish, about 75 percent died within 24 hours.

The highest concentrations of PEITC used in the research may be achieved through diets rich in broccoli and watercress.
Bonnie and Steve: Well, well, well. It only took decades for a journal to publish a study showing that the term healthy food means different things depending upon individual needs.

We have dedicated our lives to adhering to the philosophy that "we are not one-size-fits-all". This is even true when it comes to healthy foods, as shown in a recent study from the journal Cell.

You cannot believe the look on people's faces when we tell them that turmeric can be poison for some, yet wonderful for others. When all of your friends rave about it, of course you want to do it as well. But if you are salicylate intolerant, you could be doing great harm to yourself.

This is why we have always said that you have to treat eating style as something that is completely unique to you. Your epigenetics and genetics are much different from others around you. The same goes for dietary supplements, beverages, cosmetics, and anything else you put in, or on, your body.

In the Cell study, researchers found that different people reacted differently to the same foods from a glycemic standpoint. We have found this to be the case depending upon numerous variables, including gut health, epigenetics, genetics, blood type, among others.

This study got a lot of traction. We cannot get enough of seeing quotes like "doctors could be more effective by recommending a personalized nutrition plan to a patient".
Eat Breakfast for Blood Sugar Balance
Steve: A new study in Diabetes Care showed that skipping breakfast led to higher glycemic index response and reduced levels of insulin, C-peptide, and iGLP-1 after lunch and dinner, whereas breakfast consumption led to a reverse metabolic state (this is a good thing). This impaired insulin secretion after lunch and dinner also worsened glucose levels. 

Researchers also suggested that the effect of the circadian clock on glucose homeostasis might play an important role in this phenomenon. Skipping breakfast disrupts the normal meal schedule and prolonged fasting period, which may worsen postprandial glycemic level throughout the day.

These findings emphasize the importance of having breakfast in the morning to prevent adverse complications in those who have, or those with a family history of blood sugar disorders, including hypoglycemia, type 2, and type 1 diabetes.
Targeting Cancer Stem Cells
Bonnie: According to a review inInternational Journal of Molecular Sciences, the following 10 natural substances have been demonstrated to be the most effective chemopreventive dietary agents against cancer stem cells:
  1. Epigallocatechin-3-gallate (EGCG): From green tea extract
  2. Curcumin: The primary polyphenol in turmeric root
  3. Resveratrol: A phytochemical found in grapes, peanuts, Japanese knotweed
  4. Lycopene: A red carotenoid found in watermelon, pink grapefruit, and tomatoes
  5. Pomegranate extracts
  6. Luteolin: A flavonoid found in peppers and various green vegetables
  7. Genistein: A phytochemical found in soy, red clover, and coffee
  8. Piperine: A phytochemical found in black pepper
  9. Beta-carotene: An orange carotenoid found in various vegetables
  10. Sulforaphane: A sulfurous phytochemical found in Cruciferous vegetables
The fact that these phytochemicals can selectively target cancer stem cells is, according to the authors, "a milestone in the improvement of cancer treatment because the synthetic anticancer drugs that are currently used are often highly toxic for healthy organs and weakens the patient's immune system."
Prescription Medication Use Is Waning?
Bonnie: On the contrary. Big Pharma is getting exactly what it wants. A significantly higher number of Americans are using prescription drugs now than were a decade ago.

The study, which appeared in last month's JAMA, shows that eight of the 10 most commonly used drugs in 2011-2012 were used to treat components of the cardiometabolic syndrome, including hypertension, diabetes, and dyslipidemia. Another is a proton-pump inhibitor used for gastroesophageal reflux.

These are long-term lifestyle diseases, which means patients are prescribed to take these medications for decades.

Even worse news: the prevalence of polypharmacy -- the use of five or more prescription drugs at once -- increased from 8 percent to 15 percent. In addition, the percentage of adults reporting use of any prescription drugs increased from 51% in 1999-2000 to 59% in 2011-2012.

BrandBuzzBrand Buzz
Almond Mini Tart Shells for dessert-lovers seeking Gluten-Free, Paleo and Vegan options during the holidays! Exclusively in a Whole Foods Market location near you.
Comes in coconut oil flavor as well.
BPA and Aluminum-Free. Great gift idea that comes in all shapes, sizes, and temperatures!
Hydro Flask
Allergy to Body Care Ingredient on the Rise
Steve: The prevalence of contact allergy to methylisothiazolinone (MI) and methylchloroisothiazolinone-methylisothiazolinone (MCI-MI) is increasing, according to a study from JAMA Dermatology. 

Over a period of two years, researchers from the Cleveland Clinic the number of patients who presented with allergic contact dermatitis rose from 2.5% to 6.8%.

The hands and face were the most commonly affected sites. Soaps, cleansers, hair care products, wet wipes, and cosmetics accounted for all the identified sources. 74% improved with allergen avoidance.

Look for this ingredient in the all the body care products you purchase. If the ingredients are not labeled, check with the company first.

In the U.S., the Cosmetic Ingredient Review panel allows MCI-MI concentrations of 7.5 ppm in leave-on products and 15 ppm in rinse-off products For MI, maximum concentrations of 100 ppm are allowed for rinse-off products. This is not acceptable.
Food on Your Counter Can Predict Weight
Bonnie: The food on your counter can predict your weight -- especially if it's cereal or soft drinks. Over 200 American kitchens were photographed to determine if the food sitting out on counters could predict the weight of the woman living in each home.

The study from Health Education and Behaviorfound that women who had breakfast cereal sitting on their counters weighed 20 lbs more than their neighbors who didn't, and those with soft drinks sitting out weighed 24 to 26 lbs more.

The good news? Those who had a fruit bowl weighed about 13 lbs less.
Butter Lettuce Salad with Fresh Cranberry Vinaigrette

c. fresh cranberries
1 T. sugar
1 tsp. grated lemon zest plus 2 T. fresh lemon juice
c. extra-virgin olive oil

2 heads of butter lettuce
2 oz. goat cheese, crumbled (1/2 cup)
c. sliced dried apricots or cherries
c. dried cranberries
c. pecans, toasted and chopped

Make the vinaigrette: In a food processor, pulse the cranberries and sugar until finely chopped. Transfer half of the cranberries to a bowl. Add the lemon zest and juice to the processor; pulse to combine. Slowly drizzle in the oil. Add the vinaigrette to the bowl.

Make the salad: Arrange the lettuce, goat cheese, fruit, and pecans on the platter. Drizzle with the vinaigrette and serve. SERVES: 12
Bonnie and Steve: If one or more of these boxes are yellow or green, then you have genetic deficiencies that may impair your ability to break down and move toxins from your body. The great thing is that you can prevent impairment with diet, nutrients.

The graphic is an example of what our clients receive when screening their methylation cycles. The results have nothing been short of incredible.

Derived from your raw genomic data provided by the genetics company 23andMe, the results reaffirm why many clients have been so vigilant about managing their diets and lifestyles. For others, the results are providing that final push to reach their goals.

The New 23andMe
With recent news that 23andMe now tests for rare genetic disease traits, heritable lifestyle traits (such as baldness and red hair), and wellness traits, getting this test is a no brainer.

While we are most interested in the raw genomic data, their new test for lactose intolerance is very helpful.

Why the Methylation Cycle? Why Now?
It was one of the major nutritional conundrums which had evaded us for years. We tried to cover all bases to help your methylation cycle, the most important pathway for detoxification of chemicals, hormones, and other unwanted environmental byproducts, but we did not have the entire map at our disposal. Now, we can pinpoint exactly if and where your cycle is impaired and fix it.

Methylation impairment can contribute to carcinogenesis, body mass gain, autoimmune disorders, to name a few.

The Process is 5 simple steps:
  1. Pay to have your genetic kit sent to your home from the lab 23andMe. You can get the test for $189 instead of $199 at this link because of your relationship with us. We have no financial interest in 23andMe.
  2. When you receive your genetic kit, follow the instructions to prepare your sample (saliva sample) and send back to 23andMe via the US Postal Service.
  3. 23andMe will email you when your results are complete.
  4. Feel free to share your disease carrier, traits, and wellness reports with us by email.
  5. Most importantly, download your raw data from 23andMe and and email the file to us. Contact us if you need help with this step.
  6. When we get your raw data file, we will upload it into our methylation database and contact you when the results are complete to make an appointment.
Why Is This Such an Incredible Opportunity?
  • In addition to the methylation data that we analyze, 23andMe maps your entire genome. This is crucial if we offer further genetic analysis on other bodily functions or for other health care providers who may require your genetic info.
  • You only need your genome mapped once!
  • 23andMe provides you with information about your ancestry. We do not delve into this aspect of your genetic results. It is completely private to you.
  • Knowing your disease carrier status, traits, and wellness genetics (like lactose intolerance) is invaluable to you and your health professionals. 23andMe has many more test in the offing as the research becomes more available.
  • Many of you have heard us refer to the MTHFR genetic mutation for pregnancy, neurological function, and detoxification. MTHFR is included in the panel, as well as every other major gene associated with the methylation pathway.
Why Did We Decide to Finally Use Genetic Testing?
  • While we feel that much of the information about the humane genome is "not ready for prime time," we feel extremely confident that the genes associated with the methylation pathway have more than enough clinical data. The pharmaceutical industry has done most of the work for us by putting billions of dollars into researching genetics and methylation so they can find out who can best metabolize and avoid side effects from their drugs!
  • As better research comes along, having your genetic information allows us to contact you when, for instance, a genetic bone health panel comes along. How can you beat that service?
Putting Your Methylation Results Into Action

Going over the results should only take about 15 minutes. This is free for NCI Well Connect Members. For non-Well Connect members, the fee is $45.

To start the process, just go to 23andMe and click on the link:
Far Infrared Sauna Therapy
It is always the right time to experience Far Infrared Sauna Therapy.


Aside from the fact that you are taking one hour out of your busy lives to relax, Far Infrared Therapy offers numerous therapeutic benefits, most importantly enhanced detoxification. Many clients use it to relieve painful joints, rev up metabolism, and remove buildup of heavy metals.


A recent study in JAMA Internal Medicine found that increased frequency of sauna bathing reduced the risk of sudden cardiac death, coronary heart disease, cardiovascular disease, and all-cause mortality.

Contact us to schedule a session.

WildCardWild Card
Poor Sleep Ups Inflammation. Two Techniques Lower It.
Steve: Poor sleep is associated with increased inflammation, which may contribute to heart disease and a variety of other ailments. A new study from Biological Psychiatry has shown that cognitive behavioral therapy and tai chi may reduce both insomnia and inflammation.

Subjects with insomnia received two hours a week of cognitive behavioral therapy over four months, the same amount of tai chi practice, and the control group, a four-month educational program about sleep hygiene, aging and insomnia.

At one year after the treatment, compared with the control group, those on cognitive behavioral therapy and tai chi had reduced blood levels of C-reactive protein and reduced production of pro-inflammatory cytokines, lower expression of genes related to inflammation, and increased expression of genes related to antibody response.
"However difficult life may seem, there is always something you can do and succeed at."
-Stephen Hawking
Wellness Session of the Month
23andMe, Pure Genomics Methylation Cycle Evaluation

One of the perks of being a NCI Well Connect Member is that you have two free 15 minute wellness coaching sessions. 


The perk comes in handy when you've gotten your 23andMe raw genetic data and want us to analyze your methylation cycle.


To schedule your free appointment with Steve, email or phone 847-498-3422. An appointment with Bonnie is $45.

ActionPlanAction Plan of the Month:
Irritable Bowel Syndrome
One of the perks of being a NCI Well Connect Member is that you can request two titles monthly from our our Action Plan Library (41 plans: total value $300). 

This comes in handy when discerning whether your digestive symptoms may be related to Irritable Bowel Syndrome.

Our new Irritable Bowel Syndrome Action Plan is the most complete self-help guide to addressing your digestive needs.

Action Plans are free by email request for NCI Well Connect Members or can be ordered separately. To activate your NCI Well Connect Membership today at 40% OFF and get your free copy, click here.
eNewsBriefseNews Briefs
WCMembershipLike What You Read Today? Get More of it With an NCI Well Connect Membership at 40% OFF Today!
NCI Logo
NCI Well Connect Membership is open to clients and non-clients of our practice!

One Year Membership Includes:
  1. Weekly eNewsletters (84 issues). We publish our long-form issue on Monday and a Mid-Week Brief on Wednesday. Our eNewsletter has been awarded Constant Contact All Star status seven years in a row to date.
  2. Self-Help Action Plans. Access to two titles per month from our self-help Action Plan Library. There are currently 41 Action Plan titles to date on all aspects of wellness, including the new Irritable Bowel Syndrome Action Plan. You can view the list here.
  3. Natural Foods Shopping List. Updated quarterly, our Natural Foods Shopping List includes only the most meticulously vetted, highest quality food and beverage products that we recommend to our clients. These include gluten-free, corn-free, and kosher pareve items.
  4. Free 15 Minute Wellness Coaching Sessions on topics such as 23andMe genetic results, Immune System, Detox, Shedding Weight, Food Cravings and Food Addiction, and any other topic of your choosing.

The approximate cost for all of this? One dollar a week! Quite a bargain for this volume of expert wellness advice.

Click here and activate your membership today!

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Get Back to Wellness
We have a multitude of options for simple fine-tuning or the toughest cases.
  • Balanced Eating 101 (focus on eating style only)
  • Full Wellness Evaluation (with bloodwork)
  • NCI Well Connect Membership
  • Food/Med/Supplement Interaction Evaluation
  • Food Intolerance Screening (with menu plan only)
  • Dietary Supplement Update
  • Wellness and Lifestyle Coaching Sessions
  • Far Infrared Sauna Treatment
  • Grocery Shopping Tours and Pantry Raids
  • Workplace Wellness Evaluations
  • Chiropractic and Acupuncture

Consulting prices range from $45 to $225. Contact us at 847-498-3422 or email for details.

Snowbirds & Out-of-Towners
Whether you leave Chicago for the winter or live out of state, don't be a stranger. Stay connected!
  • If you need Bonnie's guidance, she is only a phone call away.
  • Read our eNewsletters to reinforce your wellness plan.
  • If you need to order supplements, we ship anywhere in the United States. We use green and recycled shipping materials. We ship probiotics that require refrigeration.

Do not hesitate to contact us to serve all of your out-of town needs.

Thirty years of serving your wellness needs. We appreciate your continued patronage and support.

Have a happy, healthy day,
Bonnie, Steve, and all of us at Nutritional Concepts

Copyright 2015 Nutritional Concepts Inc.
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