NCI Well Connect: January 18, 2016
Dear Steve, 

DID YOU KNOW that a study in last week's JAMA Internal Medicine found that the class of reflux medications called Proton Pump Inhibitors (PPIs) significantly increase the risk of chronic kidney disease?

DID YOU KNOW that drinking coffee enriched with inulin may reduce feelings of hunger and boost satiety, according to a new study in The Journal of Nutrition? Two cups of coffee per day enriched with inulin was associated with reduced hunger and increased satiety two hours after ingestion compared to non­enriched coffee. How it tastes is purely subjective.

We are starting to receive some emails when clients reply directly from our eNewsletter email, Until this is completed resolved, please use

As a rule of thumb, unless on a weekend, we almost always respond to emails within 24 hours. If you do not get a response from us, email again or call 847-498-3422.

23andMe UPDATE
Some you have mentioned that you mapped your genome years ago when 23andMe first launched. If you still have access to your account, you can send us the raw genomic data and we can evaluate your genetic methylation cycle. 

Most of you are aware of that our loyalty program provides discounts at certain product purchase benchmarks. The rewards zero out every January 1. So start your orders now to gather points and discounts.

Have a happy, healthy day. Steve and Bonnie
NCI Well Connect Highlights
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Steve Minsky
From Editor Steve Minsky
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Care's Corner - Pediatric Cancer
Bonnie and Steve: recent study showing that high-dose vitamin D in elderly persons can increase risk of fracture took on a life of its own. Once again, the media did not look at the fine print.
  • The study, published in JAMA Internal Medicine, only looked at 200 men and women over age 70.
  • This meager group of subjects all had a prior fall.
  • Low-dose group received 24,000 IU of vitamin D and the other group received 60,000 IU of vitamin D for six months. During a short 12-month follow-up after the treatment period, the researchers found 66.9 percent of the 60,000 IU group experienced a fall, as opposed to just 47.9 percent of the 24,000 IU group.
  • There was no control group taking no vitamin D.
  • Medical histories, including medication intake, supplement intake, and more were never discussed or addressed.
Aside from the fact that we have never seen subjects given vitamin D in doses higher than 50,000 IU, this study is far from conclusive about anything.

Alternatively, here are a few recent studies that you didn't here about in the mainstream media.

A randomized, double blinded, three ­arm parallel design trial of vitamin D, placebo or a combination of vitamin D and probiotics in Irritable Bowel Syndrome (IBS) patients was performed. Tests revealed that vitamin D deficiency was high across different IBS symptoms: 81.8% of those with IBS with constipation, 70% of IBS with diarrhea and 81.6% of IBS with mixed bowel habits. Results also revealed a significant association between circulating vitamin D level and quality of life. The study was published in the October 2015 issue of BMC Open Gastroenterology.

Stress Fracture
At least half of patients with stress fractures who had their vitamin D levels tested had insufficient levels, according to a study published in the January-February issue of theJournal of Foot & Ankle Surgery.

They note that individuals with vitamin D deficiency only absorb approximately 10% to 15% of dietary calcium and 50% to 60% of dietary phosphorus,"thus, a decrease in bone mineralization and structural integrity can develop, with a decrease in calcium levels.

The authors recommend minimum serum vitamin D levels of at least 40 to prevent stress fractures. To get the levels up quickly, they recommend a prescription dose (usually 50,000IU D2; we like 50,000 D3 better).

For those with a serum concentration of 35 to 40, they recommend 3000 to 5000 IU daily. After vitamin D levels are adequate, patients can take a maintenance dose of at least 2000 IU daily.

Alzheimer's Disease, Upper and Lower Limb Strength, High Cholesterol, Athletic Performance, Allergies, Breast Cancer Risk are just some of the maladies that occur due to low vitamin D levels or, maladies that may improve with vitamin D supplements, according to research from last summer to the present. No mention of them in USA Today or on Good Morning America, however. You have to be journal junkies like us to find them.
Bonnie and Steve: If one or more of these boxes are yellow or red, then you have genetic deficiencies that may impair your ability to break down and move toxins from your body. You can prevent impairment with diet and nutrient modification.

The graphic is an example of what our clients receive when screening their methylation cycles. The results have nothing been short of incredible.

Derived from your raw genomic data provided by the genetics company 23andMe, the results reaffirm why many clients have been so vigilant about managing their diets and lifestyles. For others, the results are providing that final push to reach their goals.

Why the Methylation Cycle? Why Now?
It was one of the major nutritional conundrums which had evaded us for years. We tried to cover all bases to help your methylation cycle, the most important pathway for detoxification of chemicals, hormones, and other unwanted environmental byproducts, but we did not have the entire map at our disposal. Now, we can pinpoint exactly if and where your cycle is impaired and fix it.

Methylation impairment can contribute to carcinogenesis, body mass gain, autoimmune disorders, to name a few.

All it Take Is a Few Simple Steps:
  1. Pay to have your genetic kit sent to your home from the lab 23andMe. You can get the test for $179 instead of $199 at this link because of your relationship with us. We have no financial interest in 23andMe.
  2. When you receive your genetic kit, follow the instructions to prepare your sample (saliva sample) and send back to 23andMe via the US Postal Service.
  3. 23andMe will email you when your results are complete.
  4. Go to your personal page and look in two areas depending on the state of your results: 1) Click "Tools" link, scroll down to "Browse Your Data", and click the word download. Download the file to your computer and email us the file. 2) Click your name at the top right, click "Browse Raw Data," click the download button, and find the raw data file on your computer. Attach the file and email it to us.
  5. When we get your raw data file, we will upload it into our methylation database and contact you when the results are complete to make an appointment.
Why Is This Such an Incredible Opportunity?
  • In addition to the methylation data that we analyze, 23andMe maps your entire genome. This is crucial if we offer further genetic analysis on other bodily functions or for other health care providers who may require your genetic info.
  • You only need your genome mapped once!
  • 23andMe provides you with information about your ancestry. We do not delve into this aspect of your genetic results. It is completely private to you.
  • Knowing your disease carrier status, traits, and wellness genetics (like lactose intolerance) is invaluable to you and your health professionals. 23andMe has many more test in the offing as the research becomes more available.
  • Many of you have heard us refer to the MTHFR genetic mutation for pregnancy, neurological function, and detoxification. MTHFR is included in the panel, as well as every other major gene associated with the methylation pathway.
Why Did We Decide to Finally Use Genetic Testing?
  • While we feel that much of the information about the humane genome is "not ready for prime time," we feel extremely confident that the genes associated with the methylation pathway have more than enough clinical data. The pharmaceutical industry has done most of the work for us by putting billions of dollars into researching genetics and methylation so they can find out who can best metabolize and avoid side effects from their drugs!
  • As better research comes along, having your genetic information allows us to contact you when, for instance, a genetic bone health panel comes along. How can you beat that service?
Putting Your Methylation Results Into Action
Going over the results should only take about 15 minutes. This is free for NCI Well Connect Members. For non-Well Connect members, the fee is $45.

To start the process, just go to 23andMe and click on the link:
Far Infrared Sauna Therapy
It is always the right time to experience Far Infrared Sauna Therapy.


Aside from the fact that you are taking one hour out of your busy lives to relax, Far Infrared Therapy offers numerous therapeutic benefits, most importantly enhanced detoxification. Many clients use it to relieve painful joints, rev up metabolism, and remove buildup of heavy metals.


A recent study in JAMA Internal Medicine found that increased frequency of sauna bathing reduced the risk of sudden cardiac death, coronary heart disease, cardiovascular disease, and all-cause mortality.

Contact us to schedule a session.

Wellness Session of the Month
23andMe, Pure Genomics Methylation Cycle Evaluation

One of the perks of being a NCI Well Connect Member is that you have two free 15 minute wellness coaching sessions. 


The perk comes in handy when you've gotten your 23andMe raw genetic data and want us to analyze your methylation cycle.


To schedule your free appointment with Steve, email or phone 847-498-3422. An appointment with Bonnie is $45.

ActionPlanAction Plan of the Month:
Fast Mimicking Diet
One of the perks of being a NCI Well Connect Member is that you can request two titles monthly from our our Action Plan Library (41 plans: total value $300). 

This comes in handy when you are eyeing a sensible, intelligent, effective eating style to aid detoxification and weight balance.

Our new Fast Mimicking Diet Action Plan is our smart version of the calorie-restricted eating plan which gerontologists have linked to longevity.

Action Plans are free by email request for NCI Well Connect Members or can be ordered separately. To activate your NCI Well Connect Membership today at 40% OFF and get your free copy, click here.
eNewsBriefseNews Briefs
WCMembershipLike What You See? Finalize Your NCI Well Connect Membership at 40% OFF Today!
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NCI Well Connect Membership is open to clients and non-clients of our practice!

One Year Membership Includes:
  1. Weekly eNewsletters (84 issues). We publish our long-form issue on Monday and a Mid-Week Brief on Wednesday. Our eNewsletter has been awarded Constant Contact All Star status seven years in a row to date.
  2. Self-Help Action Plans. Access to two titles per month from our self-help Action Plan Library. There are currently 41 Action Plan titles to date on all aspects of wellness, including the new Irritable Bowel Syndrome Action Plan. You can view the list here.
  3. Natural Foods Shopping List. Updated quarterly, our Natural Foods Shopping List includes only the most meticulously vetted, highest quality food and beverage products that we recommend to our clients. These include gluten-free, corn-free, and kosher pareve items.
  4. Free 15 Minute Wellness Coaching Sessions on topics such as 23andMe genetic results, Immune System, Detox, Shedding Weight, Food Cravings and Food Addiction, and any other topic of your choosing.

The approximate cost for all of this? One dollar a week! Quite a bargain for this volume of expert wellness advice.

Click here and activate your membership today!

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Our Wellness Menu
We have a multitude of options for simple fine-tuning or the toughest cases.
  • Balanced Eating 101 (focus on eating style only)
  • Full Wellness Evaluation (with bloodwork)
  • NCI Well Connect Membership
  • Genetic Methylation Evaluation - NEW
  • Food/Med/Supplement Interaction Evaluation
  • Food Intolerance Screening and Menu Plan Implementation (separate fees)
  • Dietary Supplement Update
  • Wellness and Lifestyle Coaching Sessions
  • Far Infrared Sauna Treatment
  • Grocery Shopping Tours and Pantry Advice
  • Workplace Wellness Evaluations
  • Chiropractic and Acupuncture

Consulting prices range from $45 to $225. Contact us at 847-498-3422 or email for details.

Snowbirds & Out-of-Towners
Whether you leave Chicago for the winter or live out of state, don't be a stranger. Stay connected!
  • If you need Bonnie's guidance, she is only a phone call away.
  • Read our eNewsletters to reinforce your wellness plan.
  • If you need to order supplements, we ship anywhere in the United States. We use green and recycled shipping materials. We ship probiotics that require refrigeration.
Serving your individual wellness needs. We appreciate your patronage and support.

Have a happy, healthy day,
Bonnie, Steve, and all of us at Nutritional Concepts
(847) 498 3422 - main 

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