NCI Well Connect Mid-Week Brief
April 19, 2017
Dear Steve, 

DID YOU KNOW that aside from burning your esophagus, creating excess acidity, and adding fuel to potential yeast overgrowth, why else should you avoid supplementing with Apple Cider Vinegar? It pulls calcium from bone. 

Why do you think bone broth manufacturers add apple cider vinegar to their recipes? So they can more easily draw calcium from the bones!

Have a happy, healthy day. Steve and Bonnie
Why Are So Many Popping Vitamin D?

Bonnie and Steve: 
A recent article in The New York Times, "Why Are So Many People Popping Vitamin D?", was astoundingly derogatory to the advances we've made with wellness through vitamin D monitoring. The piece is so disgustingly short-sighted, it was hard to read. 

Many of the articles the New York Times publish on wellness are very well done. This piece, however, seemed to cherry-pick research, as well as the experts they interviewed.

One of the best public health advances over the last decade should not be subjected to this. If the NYT really wanted to be ahead of the curve, they would have considered newest issue, which is the genetic availability for absorbing vitamin D3.

For example, according to a recent study in the December 2016 issue of The Journal of Nutrition, there is a high inter-individual variability in vitamin D3 bioavailability that is associated with a combination of deficiencies located in or near genes involved in both vitamin D and fat metabolism. This is now something we can now test for this.

That said, the genetic component is still a minor issue compared to the bevy of successful vitamin D data that comes in waves each month.

Here's a few highlights from research published just in the several months!

Vitamin D3 deficiency in early childhood is associated with increased risk for persistent asthma, potentially through accelerated susceptibility to allergens and upper respiratory tract colonization with bacterial pathogens, according to a study from Journal of Allergy and Clinical Immunology.

A new study from Human Kinetics linked vitamin D to athletic performance, better recovery, and fewer injuries among collegiate athletes. The researchers had the athletes perform four physical tests: a vertical jump, shuttle run, triple hop and one-rep squat max. Athletes who had lower vitamin D levels (below 50) had significantly lower performance scores in every test, showing that their strength, explosiveness, speed and agility were affected.

Increasing vitamin D levels may lower risk for developing cancer in women, according to a study in the March issue of the Journal of the American Medical Association. Over four years, postmenopausal women taking 2000IU of vitamin D3 daily for 4 years had 30% lower risk of cancer than placebo.

According to a study from Scientific Reports, over a 5 year span, 68% of men aged between 42 and 60 years had blood vitamin D levels below 50. The group with the lowest levels had over a twofold risk of chronic headache in comparison to the group with the highest levels.

Heart Disease
The higher the level of vitamin D, the lower the risk of cardiovascular disease events, according to a gigantic study from the March issue of American Journal of Clinical Nutrition.

Vitamin D deficiency is associated with early markers of cardiovascular disease in overweight and obese children and adolescents, according to new research presented at ENDO 2017, the annual scientific meeting of the Endocrine Society.

Inflammatory Bowel Disease
Low vitamin D levels may reduce the chances of success of treatment for inflammatory bowel diseases (IBD) such as colitis and Crohn's, according to a study in Alimentary Pharmacology & Therapeutics.

The Irritable Bowel Syndrome population exhibits significant levels of vitamin D insufficiency and would benefit from screening and supplementation, according to editors in BMC Open Gastroenterology. The impact of IBS on quality of life may be reduced by optimal vitamin D levels.

In the April issue of The Journal of Nutrition, researchers state that blood vitamin D3 levels were was positively associated with telomere length in middle-aged participants (aged 40-59 years), suggesting that decreased vitamin D3 concentrations are associated with genomic instability, and potentially shorter lifespan.

Multiple Sclerosis
Babies born with low levels of vitamin D may be more likely to develop multiple sclerosis later in life than babies with higher levels of vitamin D, according to a study in the November 2016 issue of Neurology.

Muscle Strength
A study from PLOS One has shown that increasing the levels of vitamin D can help to optimize muscle strength in women especially.

Children of mothers who took vitamin D during pregnancy with resultant high levels of the vitamin in the umbilical blood have fewer symptoms of ADHD at the age of 2.5 years, according to a new study from The Australia & New Zealand Journal of Psychiatry. And for every 10 nmol/L increase in the vitamin D concentration in umbilical blood, the risk for the ADHD symptoms fell 11%.

A study from the March issue of Clinical Endocrinology provides the first evidence of an inverse relationship between maternal vitamin D3 and fetal serotonin concentrations. We propose that maternal vitamin D deficiency increases fetal serotonin concentrations and thereby contributes to longer-term neurocognitive impairment in infants and children.

In the June issue of American Journal of Clinical Nutrition, researchers observed a protective association of vitamin D3 concentration above 75 and a reduced risk of uteroplacental dysfunction as indicated by a composite outcome of small for gestational age and pre-eclampsia.

When women go off birth control pills, their vitamin D levels may drop, according to research from the National Institutes of Health. And while there's no good time in life to be vitamin D deficient, lacking adequate levels of the vitamin is particularly dangerous during pregnancy, when women need more D to support the formation of the fetal skeleton.

Statin Side-Effects
Patients with myalgia were able to tolerate statin therapy after vitamin D supplementation, according to a study in the October 2016 issue of Journal of Pharmacy Practice. Replenishing low vitamin D in patients with statin-induced myopathy appears to be an effective strategy in improving medication adherence and subsequently preventing cardiovascular and mortality events.
Make Your Own Snack Bar

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New Genetics Wellness Panel!
Weight Maintenance, Metabolic Health

Bonnie and Steve: 
It only takes a few simple steps to get individualized genetic nutritional support. Test your genome. We translate the results in a way you can understand. We target your individualized needs with nutritional support that can be easily implemented.

NCI Well Connect Member Benefits
One Year Membership Includes:
  1. Award-Winning eNewsletters. We publish our long-form issue on Monday and a mid-week brief on Wednesday. Recent preview issue here.
  2. Self-Help Action Plans. Access to two titles per month from our self-help Action Plan Library. There are currently 43 Action Plan titles to date on all aspects of wellness, including the new Heal Your Headache Action Plan. You can view the full library of titles here.
  3. Natural Foods Shopping List. Updated quarterly, our Natural Foods Shopping List includes only the most meticulously vetted, highest quality food and beverage products that we recommend to our clients. These include gluten-free, corn-free, and kosher pareve items.
  4. 30 Minutes Free Pure Genomics Analysis & Coaching (Consult with Steve; Bonnie's consult would be separate).
The approximate cost for all of this? Less than one dollar a week!
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Have a happy, healthy day,

Bonnie, Steve, Carolyn, Lilo, Elizabeth, Sharron, and Jeannie
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