NCI Well Connect Mid-Week Brief
August 31, 2016
Dear Steve, 

DID YOU KNOW that two-thirds of women receiving medication for osteoporosis potentially did not need treatment, according to a recent study in JAMA Internal Medicine? In fact, half of these women with possibly inappropriate prescriptions were younger and without risk factors that would have indicated screening.

Today through Labor Day, get our August and September sale items!

You can still phone, email, or place web orders to take advantage of our double sale, but they will not ship until Tuesday, September 6th.

Have a happy, healthy day. Steve and Bonnie
Why Are Docs Not Prescribing Calcium?
Bonnie and Steve: Just last week, two female clients said their doctors told them to stop taking supplemental calcium based on a recent study. This stance, coming from the same profession who overprescribed supplemental calcium, and caused irreparable harm in women for decades, is dead wrong.

We were vehemently against the policy of prescribing the one-size-fits-all 1500 mg. supplemental calcium for women, just as we are vehemently against those who now say we should not take any supplemental calcium.

As it always is, and always will be, the source and amount of calcium, or any supplement for that matter, should be based upon individual needs.

If you need more ammunition to use if your doctor comes at you with the no calcium stance, it has been found to be essential for learning and memory.

Learning and Memory
In a new study from Cell Reports, scientists offered new insights how calcium in mitochondria, the powerhouse of all cells, can impact the development of the brain and adult cognition.

Blocking a channel that brings calcium to the mitochondria, called "mitochondrial calcium uniporter," causes memory impairment. This is why calcium channel blocker medications have numerous side effects, especially in older persons.

In addition, when there is calcium deficiency, not enough is being transported into the mitochondria, and the same memory impairment issue can occur. Deficiency occurs when there is malabsorbed, or not enough, calcium from food and supplements.

As we have written several times already this year, calcium is a crucial part of one's supplement regimen, when taken in the proper dosage and form.
May 2016
Research presented at the World Congress on Osteoporosis, involved 502,664 men and women with an average age of 58 years. After 7 years of follow-up, there were no associations between the use of calcium supplements and risk of incident hospital admission with ischemic heart disease, any cardiovascular event, or death versus those with no calcium supplementation intake.

While we are encouraged by this study, we still stick with our belief that for most individuals, between 250 mg. and 800 mg. supplemental calcium is considered the "safe zone". Finally, supplemental calcium must always be accompanied by vitamin D3 and magnesium glycinate.

February 2016
A study in American Journal of Clinical Nutrition provided fascinating results on the largest and longest study ever performed on subjects taking calcium supplements and their mortality.

Not surprisingly, the results echo much of what we have said: they are beneficial for women and not beneficial for men, especially in large doses.

Roughly 180,000 men and women for followed for 17.5 years. Dietary and supplemental calcium intake was tabulated from the start through the end of the study.

Calcium from food alone had no measurable impact in men or women.

Men who took more than 1000 mg. or more of supplemental calcium during this period had a slight increased risk of all-cause mortality, much of the risk from CVD-related outcomes. In the rare instances where we recommend calcium for men, it is never even close to 1000 mg., unless there is an acute, short-term situation.

For women, there were reductions in all-cause mortality at every calcium dosage level: 1-500 mg., 500 to 1000 mg., and 1000 mg. or more. Mortality from cancer, especially colorectal and breast, was lower in all categories. Mortality from cardiovascular disease, especially from ischemic heart disease at all dosage levels, and stroke in lower dosages, were especially significant. Finally, in all other mortality causes, the risk was lower for all calcium dosages.

This should be reaffirming to many women. And for any men still taking large doses of calcium, unless specifically recommended for an acute situation, see a licensed professional about lowering dramatically, or eliminating it altogether.

While this study is not the end of the calcium discussion, it mirrors much of what we love to see in supplement studies: large number of subjects over a long period of time.

Don't forget that calcium does it's best work when accompanied with vitamin D and absorbable magnesium. Please do not ever take calcium alone.

June 29, 2016
Ethnographic and anthropological studies indicate that adult human hunter-gatherers consumed most of their calcium in the form of bones from animals, such as small and large mammals, birds, fish and reptiles. We are genetically adapted to consume a large proportion of our dietary calcium from bones, where calcium is absorbed along with a matrix of nutrients including magnesium, phosphorus, strontium, zinc, iron, copper, collagen protein, aminoglycans and osteocalcin, all of which also support robust bone formation. 

While consuming animal bones may not be practical in the modern age (except for those who consume sardines with bones), taking a supplement that mirrors the bone matrix is highly recomended.

According to a study in the June issue of Open Heart, ingestion of microcrystalline hydroxyapatite (supplemental calcium source that mirrors the bone matrix; you may know it as MCHC or MCHA) produces less of an acute spike in blood calcium levels compared to soluble calcium salts typically used in standard supplements. Hydroxyapatite also stimulates bone osteoblast cells and contains virtually all the essential building blocks needed to construct bone tissue.

Taking a calcium supplement from carbonate, which is sourced from rocks, and citrate, which is sourced from corn-based citric acid, do not have the same absorption capability.

The addition of magnesium and vitamin D to a whole bone supplement further enhances its effectiveness.

Finally, we can get bioavailable sources of calcium from specific foods, as evidenced by the image above. Leafy greens are particularly wonderful because they contain, calcium, magnesium, and vitamin K.
Novel Method to Speed Up Muscle Healing
This article is reserved for NCI Well Connect Members.
Future of Genetics & Wellness Is Now
Bonnie and Steve: It only takes a few simple steps to get individualized genetic nutritional support. Test your genome. We translate the results in a way you can understand. We target your individualized needs with nutritional support that can be easily implemented.

NCI Well Connect Membership
One Year Membership Includes:
  1. Weekly eNewsletters (84 issues). We publish our long-form issue on Monday and a Mid-Week Brief on Wednesday. Recent preview issue here.
  2. Self-Help Action Plans. Access to two titles per month from our self-help Action Plan Library. There are currently 42 Action Plan titles to date on all aspects of wellness, including the new Eye-Mazing Vision Protection Action Plan. You can view the full library of titles here.
  3. Natural Foods Shopping List. Updated quarterly, our Natural Foods Shopping List includes only the most meticulously vetted, highest quality food and beverage products that we recommend to our clients. These include gluten-free, corn-free, and kosher pareve items.
  4. 30 Minutes Free Pure Genomics Analysis & Coaching (Bonnie's services are separate).
The approximate cost for all of this? Less than one dollar a week!
We appreciate your continued patronage and support.

Have a happy, healthy day,
Bonnie, Steve, Carolyn, Lilo, Elizabeth, and Jeannie
(847) 498 3422

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